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Age changes everything

Cough and difficulty breathing, at four ages

Read across, then answer.

Airway calibre, the viruses that circulate, and the diseases that present change with age; the phrase 'difficulty breathing' means bronchiolitis in an infant and asthma in a schoolchild.

6 weeks

Apnea, bronchiolitis, pertussis, and the cardiac lesion that presents as breathlessness.

Differential

  1. Bronchiolitis (coryza, then cough, wheeze and crackles, poor feeding)
  2. Pertussis (paroxysms, apnea, no fever)
  3. Pneumonia
  4. Congenital heart disease presenting with heart failure (sweating with feeds, poor growth)
  5. Sepsis

What changes

Infants under about 3 months with bronchiolitis, especially if premature, are at risk of apnea and are admitted with a low threshold. Ask about feeding, colour changes and pauses in breathing. Examine for a murmur, hepatomegaly and the femoral pulses.

18 months

Croup, the inhaled foreign body, and the first wheeze that may become asthma.

Differential

  1. Viral-induced wheeze
  2. Croup (barking cough, stridor, worse at night)
  3. Foreign body aspiration (sudden onset, unilateral findings)
  4. Pneumonia
  5. Bronchiolitis, less typical at this age

What changes

Distinguish stridor (upper airway, inspiratory) from wheeze (lower airway, expiratory). A sudden cough while eating or playing with small objects is a foreign body until a bronchoscopy says otherwise.

7 years

Asthma severity and the pneumonia behind a persistent fever.

Differential

  1. Asthma exacerbation
  2. Community-acquired pneumonia, including atypical
  3. Viral illness
  4. Anaphylaxis (if sudden with urticaria)
  5. Pneumothorax in the tall thin adolescent-to-be

What changes

Grade the asthma by the ability to speak, the chest movement, the saturation and the response to bronchodilator. A silent chest is severe, not better.

16 years

Adult diagnoses arrive: pneumothorax, pulmonary embolism with risk factors, vaping-related lung injury, and the anxiety diagnosis that must be made last.

Differential

  1. Asthma
  2. Pneumonia
  3. Spontaneous pneumothorax
  4. Pulmonary embolism (contraception, immobility, thrombophilia)
  5. Vaping-associated lung injury
  6. Panic or hyperventilation, by exclusion

What changes

Take the adult dyspnea history, including contraception, substances and vaping, in private. Apply adult vital sign ranges.

Which feature most reliably separates croup from bronchiolitis in a coughing 18-month-old?

The adult frame, for contrast